Biological Activity
Yohimbine is a potent and relatively nonselective alpha 2-adrenergic receptor (AR) antagonist, with IC50 of 0.6 μM.
Chemical Information
Molecular Weight | 354.44 |
CAS Number |
146-48-5 |
Solubility (25°C) | DMSO 5 mg/mL |
Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
References
[1] Guanqun Zhan, et al. Cytotoxic Yohimbine-Type Alkaloids from the Leaves of Rauvolfia vomitoria
[2] Nevio Cimolai, et al. Yohimbine use for physical enhancement and its potential toxicity